We have a new paper out. It’s about how chromosomes get shared during cell division. The paper in a nutshell In science-speak Misaligned chromosomes outside the exclusion zone become ensheathed in multiple layers of endomembranes. This event consigns the chromosome to missegregation and generates a micronucleus. In normal language Cells can make mistakes when they divide. A […]
Tag: cancer
Culture Move: new preprint on cell migration
We have a new preprint out. This is a short post to describe our findings and highlight some of the software I developed for analysing cell migration and cell shape data. Intracellular nanovesicles mediate integrin trafficking during cell migration bioRxiv doi: 10.1101/2020.08.19.257287 It is mainly the work of Gabrielle Larocque with help from Penny La-Borde […]
Fusion confusion: new paper on FGFR3-TACC3 fusions in cancer
We have a new paper out! This post is to explain what it’s about. Cancer cells often have gene fusions. This happens because the DNA in cancer cells is really messed up. Sometimes, chromosomes can break and get reattached to a different one in a strange way. This means you get a fusion between one […]
Parallel lines: new paper on modelling mitotic microtubules in 3D
We have a new paper out! You can access it here. The people This paper really was a team effort. Faye Nixon and Tom Honnor are joint-first authors. Faye did most of the experimental work in the final months of her PhD and Tom came up with the idea for the mathematical modelling and helped to […]