We have a new paper out. It’s about how chromosomes get shared during cell division. The paper in a nutshell In science-speak Misaligned chromosomes outside the exclusion zone become ensheathed in multiple layers of endomembranes. This event consigns the chromosome to missegregation and generates a micronucleus. In normal language Cells can make mistakes when they divide. A […]
Tag: mitosis
Dividing Line: not so simple division in ctenophores
This wonderful movie has repeatedly popped up into my twitter feed. It was taken by Tessa Montague and is available here (tweet is here). The movie is striking because of the way that cytokinesis starts at one side and moves to the other. Most model systems for cell division have symmetrical division. Rob de Bruin […]
Parallel lines: new paper on modelling mitotic microtubules in 3D
We have a new paper out! You can access it here. The people This paper really was a team effort. Faye Nixon and Tom Honnor are joint-first authors. Faye did most of the experimental work in the final months of her PhD and Tom came up with the idea for the mathematical modelling and helped to […]
Division Day: using PCA in cell biology
In this post I’ll describe a computational method for splitting two sides of a cell biological structure. It’s a simple method that relies on principal component analysis, otherwise known as PCA. Like all things mathematical there are some great resources on the web, if you want to understand this operation in more detail (for example, this great […]
Sticky End
We have a new paper out! You can access it here. The work was mainly done by Cristina Gutiérrez Caballero, a post-doc in the lab. We had some help from Selena Burgess and Richard Bayliss at the University of Leicester, with whom we have an ongoing collaboration. The paper in a nutshell We found that TACC3 binds […]