The Digital Cell: Workflow

The future of cell biology, even for small labs, is quantitative and computational. What does this mean and what should it look like? My group is not there yet, but in this post I’ll describe where we are heading. The graphic below shows my current view of the ideal workflow for my lab. The graphic is pretty self-explanatory, but […]

The Digital Cell

If you are a cell biologist, you will have noticed the change in emphasis in our field. At one time, cell biology papers were – in the main – qualitative. Micrographs of “representative cells”, western blots of a “typical experiment”… This descriptive style gave way to more quantitative approaches, converting observations into numbers that could be objectively assessed. […]

Tips from the Blog V: Advice for New PIs

I recently gave a talk at a retreat for new PIs working at QMUL. My talk was focussed on tips for getting started, i.e. the nitty gritty of running an efficient lab. It was a mix of things I’ve been told, worked out for myself or that I’d learned the hard way. PIs are expected to be […]

My Blank Pages II: Statistics Done Wrong

I have just finished reading this excellent book, Statistics done wrong: a woefully complete guide by Alex Reinhart. I’d recommend it to anyone interested in quantitative biology and particularly to PhD students starting out in biomedical science. Statistics is a topic that many people find difficult to grasp. I think there are a couple of reasons for this […]